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1.
Chinese Journal of Biochemical Pharmaceutics ; (6): 138-140, 2017.
Article in Chinese | WPRIM | ID: wpr-509634

ABSTRACT

Objective To investigate the clinical therapeutic effect of Xianyimucao capsule on hormone level and menstrual recovery in patients with vaginal bleeding after drug abortion.Methods 102 pregnant women with drug abortion admitted in our hospital from June 2015 to December 2016 were selected and divided into two groups by random number table, the control group was given conventional hemostasis and such symptomatic treatment as anti-infection, the observation group was given Xianyimucao capsule on the basis of control group.The clinical efficacy, the levels of serum hormones and menstrual recovery before and after the treatment of the two groups were compared.Then the safety of two groups were evaluated.Results After 14 days of the treatment, the total effective rate of the observation group was 96.1%, which was significantly higher than 80.4% of the control group (P<0.05).And the serum HCG, P and E2 levels in the two groups after the treatment were significantly lower than those before the treatment (P<0.05);serum hormone levels of the observation group were significantly better than that the control group (P<0.05).Compared with the control group, the menstruation recovery of the observation group was significantly shortened (P<0.05);there was no significant difference of the first menstrual cycle and menstrual volume after the menstruation recovery between the two groups.There was no obvious adverse reaction in the two groups during meditation. Conclusion The application of fresh motherwort capsules in the treatment of vaginal bleeding after drug abortion can stop bleeding rapidly , regulate the body's hormone levels and recover normal menstruation with high safety .

2.
Chinese Journal of Biochemical Pharmaceutics ; (6): 234-236, 2017.
Article in Chinese | WPRIM | ID: wpr-509626

ABSTRACT

Objective To analyze the carbetocin combined with oxytocin for prevention of bleeding after artificial abortion .Methods 110 cases of pregnant women undergoing artificial abortion were randomly divided into observation group and control group.Observation group were treated with carbetocin combined with oxytocin treatment, the control group were treated by oxytocin treatment, the negative blood loss, menstrual recovery changes and curative effect in two groups of patients were compared.Results The total efficiency of the observation group was 96.36%, was significantly higher than the control group 78.18%, the difference was statistically significant (P14d accounted for 3.64%, significantly lower than the control group 21.82%, the difference was statistically significant (Pmenstrual volume accounted for more than 9.09%, was lower than 32.73%in the control group, the difference was statistically significant (P<0.05).The sex hormone in two groups of patients before and after the treatment had no significant difference.The progesterone level in observation group was lower than the control group, estradiol level was higher than the control group, the difference was statistically significant (P<0.05), the adverse reaction rate in control group was 12.73% compared with 7.27% in the observation group, the difference was no statistically significant.Conclusion The abortion patients after treated with carbetocin combined with oxytocin treatment can reduce the amount of vaginal bleeding, shorten the bleeding time and menstrual recovery time, safe and reliable curative effect.

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